There appears to be a connection between estrogen and body weight regulation.  With lower estrogen levels, lab animals tend to eat more and be less physically active.  Levels that are too high or too low appear to lead to fat storage.  And, lower estrogen levels may also slow down your metabolic rate (the speed  at your body converts stored energy into working energy).
“There are many eating patterns that can be used to lose weight,” says William Samuel Yancy, M.D., director of the Duke Diet and Fitness Center and associate professor of medicine at Duke University. Many have evidence behind them, whether that’s keto, Paleo, Mediterranean, vegan, or anything else. Interestingly, there’s not as much research on what works for men as there is on women, but “for men, sometimes it’s as simple as shortening the time in which you are eating to an 8- to 10-hour window a day,” says Kristin Kirkpatrick, R.D.N., consultant for Integrative and Lifestyle Medicine for the Cleveland Clinic. Even something as straightforward as not eating after 6 PM can make a big difference—one of her male clients who lost 150 pounds found that to be especially helpful, she says.
Hormonal changes are one of the main reasons that women tend to lose more muscle as they approach menopause. Diet and exercise also play a role.12 On average, adults lose 3 to 8 percent muscle every decade after age 30.13,14 By the time you reach 80, you may have about 30 percent less muscle than you had at age 20.15,16 Muscle loss over time can lead to slower RMR, increased fat, weight gain, weakness, and fractures.17
Have you noticed a little extra cushioning on your bottom, belly, and hips and increased difficulty losing those stubborn extra pounds? You are not alone. This is a common problem that women face as they are entering perimenopause and menopause. As a woman over 40 (and turning 50 this year), I understand your concerns. However, as a physician, I know that it is possible to achieve a healthy weight at this time of our lives.
As you reach mid-life, the pressures pile up. Just think of the typical stressors, like caring for kids and aging parents, facing financial burdens and dealing with the demands of a job. When you’re experiencing stress, your body responds by releasing the hormone cortisol. If your stress diminishes, your hormone levels return to normal, but if you’re experiencing ongoing stress from “adulting,” cortisol levels will remain high. This can set off a series of biological events that may lead to an increased appetite with more cravings and a propensity to store fat in your belly.
If you were very active in your younger years, you may have had some injuries.  Like a spicy pepperoni pizza does after dinner, those injuries from your carefree days can come back to haunt you.  These ghosts of injuries past show up in the form of early arthritis, bone spurs, tighter muscles, pinched nerves, etc.  After our 30’s, new injuries also take longer heal.  No wonder we slow down.
That delicious plate you just bought or cooked up might temp you to gobble it up in just a few bites, but that's probably not a good idea, says Palinski-Wade. "Eating slowly, eliminating distractions at meals, and even putting your fork down in between bites all allow you to get in touch with your body’s satiety signals and to stop eating when satisfied."
Your muscles are important for bone density, strength, and overall health. However, your body starts to lose muscle as you age. Building muscle can increase your metabolism and help you burn more calories at rest. Muscle also takes up less space than fat, so you can feel leaner and toned as you increase your muscle mass. Good options to increase your muscle mass include light weightlifting, body weight exercises, and Pilates.
Let's get down to business: If you're having a hard time achieving your weight-loss goals after 40, these 16 expert-backed tips for losing weight in your 40s are totally doable and can nudge your body in the right direction again. (And, tbh, they're wise for anyone looking to move the needle to keep in mind—not just those over 40.) You'll be on your way to a stronger, healthier you in no time.
Gluten and dairy are two of the biggest culprits behind the ever-increasing rates of chronic illness, autoimmune diseases, and obesity. Gluten has been linked to increased inflammation, leaky gut syndrome, sleep disturbances, mood fluctuations, and skin issues.21,22 Consuming dairy can lead to inflammation, gut issues, and increased risk factors for a number of health problems. Banishing both gluten and dairy is one of the number one actions I recommend for you to take control of your health and your weight. To learn more read my book, The Autoimmune Solution.
The more years we live, the higher our risk of developing a disease, especially heart disease, cancer, stroke and diabetes. All of these conditions are tied, in some way, to inflammation. A 2017 study from Georgetown showed that mindfulness meditation had a significant impact on reducing stress hormones and inflammatory proteins and a 2014 study found that just 25 minutes of meditation a day could alleviate stress levels.
Remember how we said that the more muscle you have on your body, the better your metabolism works? Having more muscle increases your resting metabolic rate (RMR). This helps you burn more calories at rest—which is what you want if you’re aiming for weight loss after 40. So if you’ve been avoiding those weight machines or dumbbells, now’s the time to dedicate yourself to strength training. It is never too late to start strength training! If it is new to you, take advantage of any free personal training sessions that might be offered when you join a local gym or health club. This is often to familiarize you with the equipment and the layout of the facility, but can be a useful tool to get you started on a routine. Of course, if you have the finances to hire a trainer for a few sessions that’s another way to go.

Another great idea it to get into a group fitness strength training class. This is a less intimidating way to get started and in most gyms you will find people of all ages and abilities attending; just ask the instructor if it is the right level for you. Strength training at home is another possibility. By joining GHU TV you are spending a minimal amount and getting the personal training of experts like Chris Freytag and others who will do the workout with you providing the expertise needed to do it correctly!  Just pick up a pair of dumbbells, bring them home and get started. Keep in mind that if you are afraid to pick up the weights you can even use your own bodyweight to build strength through moves like push-ups, lunges and squats. Strength training for as little as 20 minutes two to three times a week can build enough muscle to increase your resting metabolic rate (RMR) over time.
Before you try anything else, make sure there isn’t an underlying factor interfering with your weight loss, like a thyroid condition. Did you know that nearly 1 in 5 adults over 40 suffer from thyroid problems that can interfere with weight loss? Your thyroid is the main regulator of your body’s metabolism, so having an over or under-active thyroid gland (hyper or hypothyroidism) can truly interfere with weight loss. Talk to your doctor if you’re having trouble losing weight and also experiencing any of the following symptoms of a thyroid disorder:
Focusing on being healthy means getting about 30 minutes of moderate exercise every day. This level of exercise can keep your heart healthy and work on things like lowering your cholesterol and/or blood pressure. This is a great place to start if you're getting into exercise after a long break. There's no reason you can't start here and progress to more intense goals as you build strength and endurance.
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