As you enter your forties, you are also entering perimenopause, when levels of your sex hormones progesterone and estrogen decline. Besides regulating your menstrual cycle and reproductive functions, these hormones also impact restful sleep and relaxation. A decrease in progesterone and estrogen levels may lead to sleep disturbances, restlessness, and insomnia.1 Because changes in sleep patterns have been associated with weight gain, sleepless nights may make weight loss increasingly difficult.2
If you eat healthy and exercise regularly and still can’t lose weight, your thyroid might not be working like it should. This happens in about 5% of people, and it's most common in women and people over 60. In addition to weight gain, it can also cause fatigue, joint or muscle pain, and depression. Medications can help, so get it checked if you think it might be an issue.
If you're genetically predisposed to gain weight easily, that may be another strike against you. Even if you don't actually gain weight, you may still gain inches around the waist. This weight gain can be so frustrating, it's easy to become obsessed with losing it, starving yourself or exercising too much or maybe even looking into the latest plastic surgery procedure.
In your forties, your body may have an increasingly difficult time digesting carbohydrates, which may lead to weight gain. Living a stressful life can lead to an increase in the stress-hormone called cortisol, which can make you more prone to gaining belly fat. Estrogen loss may also lead to fat redistribution in your body and cause belly fat gain.11

Your metabolic rate naturally continues to decline 5 percent each decade once you hit 40.3 Your resting metabolic rate (RMR) determines how many calories you just to survive. It is determined by a variety of chemical reactions inside your body. These reactions rely on your mitochondrial function and sodium-potassium pumps. Your mitochondria help to create energy, while your sodium-potassium pumps generate muscle contractions and nerve impulses.4,5,6,7,8 Both of these processes become less effective over the years and slow your metabolism.9,10 If you eat more than your RMR yet lead a sedentary life, you set yourself up for weight gain.

“Instead of eating less of everything and feeling deprived, you want to replace more calorie-dense foods, such as fried foods, high-fat meats, cookies, cakes, candies (and) chips, with nutrient-rich, less calorie-dense foods, such as vegetables, fruits, salads, bean dishes, broth-based soups and whole grains like oatmeal,” said Kushner, adding that the high water and fiber content of foods like these increase their volume, making them more satisfying for fewer calories.

Chronic stress can increase cortisol in your body, and lead to high insulin levels. You may even end up craving more sugary and fatty junk food,41 resulting in more stubborn pounds and belly fat. Managing your stress will increase your overall well-being and can help with weight loss. Breathing exercises, meditation, dance, gentle exercise, journaling, and listening to uplifting music are some of my favorite ways to lower stress.

Developing good sleeping habits is crucial when it comes to weight loss.40 The exercise and dietary tips with discussed earlier can support your sleep cycle. Avoid sugary and caffeinated foods, especially as the evening approaches, so you can feel tired and calm, instead of jittery. Limit blue-light exposure in the evening by wearing amber glasses that block harmful wavelengths from electronics. Develop a night-time routine that calms you down before bedtime.
Good stress management techniques and routine exercise will have positive effects on your sleep, but you may need to take additional steps to help you sleep better. For example, be proactive about going to bed and waking up at the same time most days, and allow yourself 30 minutes to unwind and disconnect from your digital devices at night. Eating a plant-forward, mostly whole foods diet that’s low in added sugar helps, too.
If you eat healthy and exercise regularly and still can’t lose weight, your thyroid might not be working like it should. This happens in about 5% of people, and it's most common in women and people over 60. In addition to weight gain, it can also cause fatigue, joint or muscle pain, and depression. Medications can help, so get it checked if you think it might be an issue.
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