This is for your health, not your looks. Excess weight can increase the risk of inflammation, pain, and disease. As you get healthier, you will have more energy for your family, friends, and activities you love. You may be approaching midlife, however, the best is yet to come! If you follow these simple dietary, lifestyle, and mindfulness strategies, you can lose weight in midlife and face your future in your best shape yet.
Amy Myers, MD is a two-time New York Times bestselling author and an internationally acclaimed functional medicine physician. Dr. Myers specializes in empowering those with autoimmune, thyroid, and digestive issues to reverse their conditions and take back their health. In addition, she is a wife, mother, and the successful founder and CEO of Amy Myers MD®.
“There are many eating patterns that can be used to lose weight,” says William Samuel Yancy, M.D., director of the Duke Diet and Fitness Center and associate professor of medicine at Duke University. Many have evidence behind them, whether that’s keto, Paleo, Mediterranean, vegan, or anything else. Interestingly, there’s not as much research on what works for men as there is on women, but “for men, sometimes it’s as simple as shortening the time in which you are eating to an 8- to 10-hour window a day,” says Kristin Kirkpatrick, R.D.N., consultant for Integrative and Lifestyle Medicine for the Cleveland Clinic. Even something as straightforward as not eating after 6 PM can make a big difference—one of her male clients who lost 150 pounds found that to be especially helpful, she says.

However, the important takeaway here is this: The biggest factor in losing muscle is the lack of physical activity, which makes exercise a crucial component when it comes to preventing muscle loss. If you want to figure out the real deal, enter your information into a calculator to learn how many calories you really need for your age and activity level.
If you are taking the appropriate measures (e.g., eating enough of a calorie deficit for your age and body composition, stressing less, and working on strength training) and still not losing weight, and you also have other symptoms of hypothyroidism (such as constipation, fatigue, dry hair and nails), then it may be worth considering getting your thyroid levels checked," advises Dr. Peterson.

For a sustainable plan, "I don't like to hyperfocus on calories. It's important to have a high-quality diet of lean protein, whole grains, and fruits and vegetables," Dr. Stanford says. "Processed foods lead to weight gain, so the less processed the food you eat, the better." And the more satisfied you could end up being. Her example: A nice meal of salmon plus some grains and a vegetable and a salad can give you a lot more volume than a Shake Shack stop would, and would give you more of a sense of being full afterward. When it comes to the high-quality diet she advocates, "nothing is bizarre—we know that lean protein, whole grains, fruits, and vegetables are constant no matter how the guidelines for healthy eating have changed over the years," she says.
As you enter your forties, you are also entering perimenopause, when levels of your sex hormones progesterone and estrogen decline. Besides regulating your menstrual cycle and reproductive functions, these hormones also impact restful sleep and relaxation. A decrease in progesterone and estrogen levels may lead to sleep disturbances, restlessness, and insomnia.1 Because changes in sleep patterns have been associated with weight gain, sleepless nights may make weight loss increasingly difficult.2
One of the main culprits for weight gain is, of course, our hormones, which start to change right around the mid-30s and into the 40s. This change in hormones, less estrogen for women and less testosterone for men, cause the fat in our bodies fat to shift to the middle of the body while abandoning other areas of the body you could care less about. That's one reason you may get a little fluffier around the middle while other parts of you actually get smaller.
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