Hormone imbalance can also wreak havoc on your weight. Keep in mind that perimenopause and other hormone changes can start when you are in your 40s. Estrogen dominance will definitely interrupt weight loss but so will the imbalance of  cortisol, leptin and insulin. We have a great article that covers, in great detail, how these hormones affect your body. Check out Balance These 4 Hormones If You Want To Lose Weight for more information!
Eating well isn’t just about skipping out on processed junk food. It’s also about filling up your plate with clean, healthy foods that can actually assist in your weight loss. Healthy fats like those found in olive oil, avocados and nut butters nourish your body while helping you feel full longer—which means you’re less likely to overeat. Incorporating healthy sources of protein like eggs and salmon will also help you feel more satiated as well as fuel the muscles you’re building through that regular strength training we mentioned above! Hungry during the day? Keep a small pack of heatlhy almonds or other nuts in your bag to snack on in a pinch.  Just a handful will keep you satisfied until your next meal, all while providing healthy protein, fat and fiber. Don’t wait until you’re tummy is growling! Be prepared.
In your forties, your body may have an increasingly difficult time digesting carbohydrates, which may lead to weight gain. Living a stressful life can lead to an increase in the stress-hormone called cortisol, which can make you more prone to gaining belly fat. Estrogen loss may also lead to fat redistribution in your body and cause belly fat gain.11
I am 59 and have been on a injury / weight gain cycle for several years. I have never been overweight till my first accident , then I gained weight and kept gaining and now that I am almost 60 , I want that great body and high energy back. The older I get the more problems my weight causes , legs hurt , falling asleep in my chair , I am too young for that. So I am eating better and boxing , which is a great workout . I plan to sky dive for my 60th next year.
There appears to be a connection between estrogen and body weight regulation.  With lower estrogen levels, lab animals tend to eat more and be less physically active.  Levels that are too high or too low appear to lead to fat storage.  And, lower estrogen levels may also slow down your metabolic rate (the speed  at your body converts stored energy into working energy).
2. Exercise More. Contrary to what your body may want to do, you must exercise more regularly as you age, not less!  If you’re finding yourself slowing down, gradually start ramping it back up.  It’s not a good idea to go from taking an occasional walk to running a 10K.  That’s a fast track to getting an injury.  But start finding ways to fit more physical activity to your life.  The more you exercise, the more insulin sensitive you become (that’s the opposite of insulin resistant!)
Sleeping enough is important, and if your lifestyle is making you cheat sleep, then think about what you can do to get enough. Sometimes, however, biology is keeping you from enough shuteye, and it's imperative to solve that. "Untreated obstructive sleep apnea can lead to additional weight gain," says Dr. Stanford. If you are making all the right efforts to get restorative sleep and still don't feel restored, consider seeing a sleep doctor, who can drill down on the problem and help you find some solutions.
At 41, these are the things that I notice the most. My body does not bounce back as easily as it once did and I have to work a lot harder to manage my weight. Genetics play a role in the aging process, but our lifestyle choices can help dictate how well our genes treat us as we get older. After turning 40, these are six of the top lifestyle habits to focus on.

Oxidative stress occurs when the balance between free radicals in the body and our ability to fight against them is uneven, with free radicals prevailing. Free radicals can cause disease and there is an association with an increased risk of formation of free radicals as we age. That's why after a certain age, building up our defenses (through having lots of antioxidants in plants) can help reduce this imbalance and stack the cards in our defense system instead.

Have you noticed a little extra cushioning on your bottom, belly, and hips and increased difficulty losing those stubborn extra pounds? You are not alone. This is a common problem that women face as they are entering perimenopause and menopause. As a woman over 40 (and turning 50 this year), I understand your concerns. However, as a physician, I know that it is possible to achieve a healthy weight at this time of our lives.
“To achieve and maintain a healthy weight as we age, it’s imperative that we incorporate a ‘movement portfolio’ into our daily lives,” said Kushner. He explained that your portfolio should include activities of daily living (like walking, using the stairs and house cleaning), active fitness activities (like bike riding and using the elliptical machine) and resistance-training exercises. Kushner also recommended trying to reduce the time you spend doing sedentary activities like watching TV. “These targeted action steps will boost metabolism and help maintain muscle mass,” he said.
If you're genetically predisposed to gain weight easily, that may be another strike against you. Even if you don't actually gain weight, you may still gain inches around the waist. This weight gain can be so frustrating, it's easy to become obsessed with losing it, starving yourself or exercising too much or maybe even looking into the latest plastic surgery procedure.
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