Oxidative stress occurs when the balance between free radicals in the body and our ability to fight against them is uneven, with free radicals prevailing. Free radicals can cause disease and there is an association with an increased risk of formation of free radicals as we age. That's why after a certain age, building up our defenses (through having lots of antioxidants in plants) can help reduce this imbalance and stack the cards in our defense system instead.
The more years we live, the higher our risk of developing a disease, especially heart disease, cancer, stroke and diabetes. All of these conditions are tied, in some way, to inflammation. A 2017 study from Georgetown showed that mindfulness meditation had a significant impact on reducing stress hormones and inflammatory proteins and a 2014 study found that just 25 minutes of meditation a day could alleviate stress levels.
Exercise can actually increase your energy. Just three hours of exercise weekly can improve the health of menopausal women.35,36,37,38,39 You may be able to add aerobic exercise into your everyday life without even noticing it! Take a walk during lunch with your colleagues. Go for a bike ride with your family after dinner. Put some music on while cleaning the house and add some dance moves. Jump on an elliptical trainer or treadmill instead of sitting while watching your favorite show.
Unfortunately, you can't just focus on one area of your body. "Women should focus on all muscle groups in order to lose weight and build muscle because there's no such thing as spot training," Diamond reminds. "With that said, women have a tendency to gain weight in the midsection as we age and focusing on the core and a well-balanced workout will help to reshape body composition."
Many women have trouble sleeping during menopause due to hot flashes, night sweats, stress and the other fun stuff that goes along with low estrogen levels.  Migraines anyone??  The bummer is poor sleep is linked to hunger and weight gain because of two more hormones:  ghrelin (the “feed me” hormone) and leptin (the “I’m full” hormone).  Here’s a short blog I wrote on that topic.  If you’re sleep deprived, these hormones get out of whack.
Alcohol adds unnecessary calories and sugar to your diet. Drinking alcohol may also increase your appetite, leading you to consume more calories.30 When you’re under the influence of alcohol, you may also be tempted to choose less nutritious options, such as processed junk foods. I recommend reducing your alcohol consumption to an occasional glass of wine or eliminating it completely.
This is for your health, not your looks. Excess weight can increase the risk of inflammation, pain, and disease. As you get healthier, you will have more energy for your family, friends, and activities you love. You may be approaching midlife, however, the best is yet to come! If you follow these simple dietary, lifestyle, and mindfulness strategies, you can lose weight in midlife and face your future in your best shape yet.
“There are many eating patterns that can be used to lose weight,” says William Samuel Yancy, M.D., director of the Duke Diet and Fitness Center and associate professor of medicine at Duke University. Many have evidence behind them, whether that’s keto, Paleo, Mediterranean, vegan, or anything else. Interestingly, there’s not as much research on what works for men as there is on women, but “for men, sometimes it’s as simple as shortening the time in which you are eating to an 8- to 10-hour window a day,” says Kristin Kirkpatrick, R.D.N., consultant for Integrative and Lifestyle Medicine for the Cleveland Clinic. Even something as straightforward as not eating after 6 PM can make a big difference—one of her male clients who lost 150 pounds found that to be especially helpful, she says.
There appears to be a connection between estrogen and body weight regulation.  With lower estrogen levels, lab animals tend to eat more and be less physically active.  Levels that are too high or too low appear to lead to fat storage.  And, lower estrogen levels may also slow down your metabolic rate (the speed  at your body converts stored energy into working energy).
“Instead of eating less of everything and feeling deprived, you want to replace more calorie-dense foods, such as fried foods, high-fat meats, cookies, cakes, candies (and) chips, with nutrient-rich, less calorie-dense foods, such as vegetables, fruits, salads, bean dishes, broth-based soups and whole grains like oatmeal,” said Kushner, adding that the high water and fiber content of foods like these increase their volume, making them more satisfying for fewer calories.

When you’re under-rested, your appetite-regulating hormones get short-circuited, so your appetite goes into overdrive, but the hormones that tell you you’re full don’t kick in promptly. Studies also suggest that when you’re sleep-deprived, it alters the way you think about food, so you have stronger cravings for sweets and other less healthful eats.
To jumpstart your weight loss, the biggest focus should be to develop habits that will help you build or maintain your muscle mass. "The most effective way that women over 40 can boost their metabolism is by building muscle through weight-lifting and resistance training," says Dr. Peterson (more on that to come). But nutrition and sleep habits also play a role here.
This is a great article. I appreciate all this insight and help as hitting 40 a few years ago was a shock to my body for sure. I would also add to your stress reducing ideas to spend some time reading the Psalms in the Bible. The God who created you longs to take your burdens and teach you how to stop trying to solve all your problems on your own. He is there to show you the way to stress reduction and a while new/better way of doing life. If you don’t know God or how you can start a personal 1-on-1 relationship with Him, check out some of these helpful apps in the App Store: Knowing God Personally (by Power to Change), God Tools (by Cru), Life Conversation Guide (by North American Mission Board), or talk to a pastor at a local Christian church in your neighborhood. My rule of thumb is that while working to take care of my physical body throughout my lifetime, I never want to neglect my soul that will continue on for all eternity.
I am 59 and have been on a injury / weight gain cycle for several years. I have never been overweight till my first accident , then I gained weight and kept gaining and now that I am almost 60 , I want that great body and high energy back. The older I get the more problems my weight causes , legs hurt , falling asleep in my chair , I am too young for that. So I am eating better and boxing , which is a great workout . I plan to sky dive for my 60th next year.

Gluten and dairy are two of the biggest culprits behind the ever-increasing rates of chronic illness, autoimmune diseases, and obesity. Gluten has been linked to increased inflammation, leaky gut syndrome, sleep disturbances, mood fluctuations, and skin issues.21,22 Consuming dairy can lead to inflammation, gut issues, and increased risk factors for a number of health problems. Banishing both gluten and dairy is one of the number one actions I recommend for you to take control of your health and your weight. To learn more read my book, The Autoimmune Solution.

People naturally lose muscle after 40, especially women after menopause. Because muscle burns more calories than fat, this can slow down your metabolism and make it harder to shake those stubborn pounds. Strength-training exercises -- lifting weights or doing body-weight exercises, like push-ups and squats -- at least twice a week can help you keep those muscles.
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