Guys often wonder whether a dip in testosterone is at the root of their weight gain, says Dr. Stanford. "When men develop overweight and obesity, they tend to have a drop in testosterone that leads to a drop in energy and more retention of adipose tissue,” she says. The excess adipose tissue drives testosterone down. But taking testosterone isn’t usually the answer. “That’s not the underlying problem. Once we normalize the weight, the testosterone normalizes," she explains.
"One of the reasons that it's difficult to lose weight in your 40s is that you are beginning to lose muscle mass, so the composition of your body tissue changes," explains Keri Peterson, MD, Women's Health advisor. "Having higher muscle mass raises your metabolism, so your body burns more calories." So when you're dealing with the opposite—less muscle mass—that means a slower metabolism. Argh.
“There are many eating patterns that can be used to lose weight,” says William Samuel Yancy, M.D., director of the Duke Diet and Fitness Center and associate professor of medicine at Duke University. Many have evidence behind them, whether that’s keto, Paleo, Mediterranean, vegan, or anything else. Interestingly, there’s not as much research on what works for men as there is on women, but “for men, sometimes it’s as simple as shortening the time in which you are eating to an 8- to 10-hour window a day,” says Kristin Kirkpatrick, R.D.N., consultant for Integrative and Lifestyle Medicine for the Cleveland Clinic. Even something as straightforward as not eating after 6 PM can make a big difference—one of her male clients who lost 150 pounds found that to be especially helpful, she says.

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