Oxidative stress occurs when the balance between free radicals in the body and our ability to fight against them is uneven, with free radicals prevailing. Free radicals can cause disease and there is an association with an increased risk of formation of free radicals as we age. That's why after a certain age, building up our defenses (through having lots of antioxidants in plants) can help reduce this imbalance and stack the cards in our defense system instead.
Hormone imbalance can also wreak havoc on your weight. Keep in mind that perimenopause and other hormone changes can start when you are in your 40s. Estrogen dominance will definitely interrupt weight loss but so will the imbalance of  cortisol, leptin and insulin. We have a great article that covers, in great detail, how these hormones affect your body. Check out Balance These 4 Hormones If You Want To Lose Weight for more information!
Healthy fats such as avocados, coconut oil, extra virgin olive oil, avocado oil, and ghee have a number of benefits. These include reducing the risk of heart attack, coronary artery disease, high cholesterol, high blood pressure, cancer, diabetes, and metabolic syndrome.23,24,25,26,27 They can keep you satisfied longer, reducing the risk of overeating and snacking. Healthy eating doesn’t mean deprivation! Healthy fats taste good and improve your brain health, and so may help you feel emotionally satisfied, lowering the risk of emotional eating.28
To jumpstart your weight loss, the biggest focus should be to develop habits that will help you build or maintain your muscle mass. "The most effective way that women over 40 can boost their metabolism is by building muscle through weight-lifting and resistance training," says Dr. Peterson (more on that to come). But nutrition and sleep habits also play a role here.

Before you try anything else, make sure there isn’t an underlying factor interfering with your weight loss, like a thyroid condition. Did you know that nearly 1 in 5 adults over 40 suffer from thyroid problems that can interfere with weight loss? Your thyroid is the main regulator of your body’s metabolism, so having an over or under-active thyroid gland (hyper or hypothyroidism) can truly interfere with weight loss. Talk to your doctor if you’re having trouble losing weight and also experiencing any of the following symptoms of a thyroid disorder:
There appears to be a connection between estrogen and body weight regulation.  With lower estrogen levels, lab animals tend to eat more and be less physically active.  Levels that are too high or too low appear to lead to fat storage.  And, lower estrogen levels may also slow down your metabolic rate (the speed  at your body converts stored energy into working energy).
Exercise can actually increase your energy. Just three hours of exercise weekly can improve the health of menopausal women.35,36,37,38,39 You may be able to add aerobic exercise into your everyday life without even noticing it! Take a walk during lunch with your colleagues. Go for a bike ride with your family after dinner. Put some music on while cleaning the house and add some dance moves. Jump on an elliptical trainer or treadmill instead of sitting while watching your favorite show.
"One of the reasons that it's difficult to lose weight in your 40s is that you are beginning to lose muscle mass, so the composition of your body tissue changes," explains Keri Peterson, MD, Women's Health advisor. "Having higher muscle mass raises your metabolism, so your body burns more calories." So when you're dealing with the opposite—less muscle mass—that means a slower metabolism. Argh.

Let me see if this sounds familiar: you’re over forty and exercising regularly. You eat a balanced diet and pass on dessert at parties. And yet, you can’t get rid of those extra pounds. If this scenario describes you, you’re not imagining things. Oftentimes, losing weight does get harder as you get older, even if you’re someone who has always been able to easily manage your weight with diet and exercise. Starting at age 30, most people begin to lose about half a pound of muscle per year. What does this have to do with weight loss? The more muscle you have on your body, the better your metabolism works. So it’s not just in your head: losing weight after 40 is more difficult than when you were younger. But you don’t have to feel like weight loss after 40 is impossible. Here are six ways to lose that extra weight after 40.
Unfortunately, you can't just focus on one area of your body. "Women should focus on all muscle groups in order to lose weight and build muscle because there's no such thing as spot training," Diamond reminds. "With that said, women have a tendency to gain weight in the midsection as we age and focusing on the core and a well-balanced workout will help to reshape body composition."
While quality zzz’s can become ever-elusive as you age from busy schedules, back pain, or menopausal symptoms like hot flashes or insomnia, getting enough sleep is an essential component to weight loss. A good night’s sleep actually burns calories! Plus, studies have shown a strong link between lack of sleep and over-eating the following day. This is because the hormones ghrelin and leptin are thrown out of whack when you don’t get enough sleep, leaving you feeling more hungry but less satiated at every meal, which leads to overeating.
Let me see if this sounds familiar: you’re over forty and exercising regularly. You eat a balanced diet and pass on dessert at parties. And yet, you can’t get rid of those extra pounds. If this scenario describes you, you’re not imagining things. Oftentimes, losing weight does get harder as you get older, even if you’re someone who has always been able to easily manage your weight with diet and exercise. Starting at age 30, most people begin to lose about half a pound of muscle per year. What does this have to do with weight loss? The more muscle you have on your body, the better your metabolism works. So it’s not just in your head: losing weight after 40 is more difficult than when you were younger. But you don’t have to feel like weight loss after 40 is impossible. Here are six ways to lose that extra weight after 40.
While it seems like ankle weights should help our leg muscles tone faster than without the weights, our legs aren’t designed to carry around heavy feet. There is more risk for injury of tendons and ligaments than toning leg muscles. If you want to focus on leg toning, your best option is some body weight workouts or exercises such as lunges with weights.
One of the main culprits for weight gain is, of course, our hormones, which start to change right around the mid-30s and into the 40s. This change in hormones, less estrogen for women and less testosterone for men, cause the fat in our bodies fat to shift to the middle of the body while abandoning other areas of the body you could care less about. That's one reason you may get a little fluffier around the middle while other parts of you actually get smaller.
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